Lipomyelomeningocele

Lipomyelomeningocele (lipoMMC) is a closed neural tube defect in which the surface lipomatous tissue is attached to the spinal cord.LipoMMC can present as only a skin lesion without any neurological deficits or with neurological disorders like lower-extremity weakness and/or deformity and bladder dysfunction, scoliosis secondary to a tethered cord. Risk factors are maternal periconceptional folic acid deficiency, some genetic and environmental factors, maternal obesity & maternal dietary glycemic intake, vitamin B 12 deficiency, maternal hyperinsulinemia and use of antiepileptic medications during pregnancy.